Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | BCR | P11274 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17072086 | 0.92 | ESR1 (0.56) | ABL1ABCB1BCRCA2ESR1 | |
| SCHEMBL17072098 | 0.92 | ESR1 (0.56) | ABL1ABCB1BCRCA2ESR1 | |
| SCHEMBL26088590 | 0.85 | CA2 (0.62) | CA2ESR1SLC28A3LTA4HEPHX2 | |
| SCHEMBL3535251 | 0.85 | CA2 (0.54) | CA2LTA4HEPHX2CYP4A11ALDH1A1 | |
| SCHEMBL17072101 | 0.84 | ESR1 (0.56) | ABL1ABCB1BCRCA2ESR1 | |
| SCHEMBL378288 | 0.83 | CA2 (0.60) | ABL1ABCB1BCRCA2ESR1 | |
| SCHEMBL19730229 | 0.82 | MEN1 (0.46) | ABL1ABCB1BCRCA2ESR1 | |
| SCHEMBL19116667 | 0.79 | CA2 (0.50) | CA2SLC28A3LTA4HEPHX2IGF1R | |
| SCHEMBL14884583 | 0.78 | CHKA (0.47) | CA2LTA4HEPHX2IGF1RALOX15 | |
| SCHEMBL19100748 | 0.78 | RXRA (0.44) | CA2LTA4HEPHX2IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2682448-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-04-20 | — | — | EP | disclosed |
| EP-2682448-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-04-20 | — | — | EP | disclosed |
| US-9133395-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9133395-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9133395-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-09-15 | — | — | US | disclosed |