Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 10/20 | 0.40 |
| ▸ | LPL | P06858 | 9/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24058035 | 0.88 | DGAT1 (0.51) | DGAT1LIPGLPLROCK1EGFR | |
| SCHEMBL20361801 | 0.86 | LIPG (0.43) | DGAT1LIPGLPLROCK1 | |
| SCHEMBL17081762 | 0.83 | LPL (0.44) | LIPGLPLROCK1EGFR | |
| SCHEMBL12982927 | 0.82 | ROCK1 (0.48) | DGAT1LIPGLPLROCK1KEAP1 | |
| SCHEMBL3515052 | 0.79 | DGAT1 (0.56) | DGAT1LIPGLPLKEAP1NFE2L2 | |
| SCHEMBL20294856 | 0.79 | DGAT1 (0.55) | DGAT1LIPGLPLTDP1L3MBTL1 | |
| SCHEMBL20361206 | 0.78 | LIPG (0.46) | DGAT1LIPGLPLROCK1 | |
| SCHEMBL31008257 | 0.78 | PIK3CG (0.41) | DGAT1LIPGLPLMAPT | |
| SCHEMBL29135246 | 0.78 | PIK3CG (0.41) | DGAT1LIPGLPLMAPT | |
| SCHEMBL1331278 | 0.78 | LPL (0.42) | DGAT1LIPGLPLROCK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2682448-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-04-20 | — | — | EP | disclosed |
| US-9133395-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9133395-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-09-15 | — | — | US | disclosed |