Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20213576 | 0.87 | DYRK1A (0.37) | DYRK1ATERTCDK4CCND1CHEK1 | |
| SCHEMBL12270275 | 0.83 | DYRK1A (0.38) | DYRK1ATERTPARP1CDK4CCND1 | |
| SCHEMBL929859 | 0.79 | DYRK1A (0.39) | DYRK1ATERTPARP1CHEK1AURKA | |
| SCHEMBL12270262 | 0.74 | GPR3 (0.41) | CDK4CCND1LIMK1CDK5KDM4E | |
| SCHEMBL16429543 | 0.73 | TERT (0.35) | DYRK1ATERTPARP1CDK4CCND1 | |
| SCHEMBL12270158 | 0.72 | KDM4E (0.37) | KDM4E | |
| SCHEMBL16429395 | 0.72 | TERT (0.34) | DYRK1ATERTPARP1CDK4CCND1 | |
| SCHEMBL12270422 | 0.71 | GPR3 (0.43) | CDK4CCND1NTRK1LIMK1CDK5 | |
| SCHEMBL24129763 | 0.70 | KDM4E (0.34) | DYRK1AKDM4E | |
| SCHEMBL2036883 | 0.70 | GPR35 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9136483-B1 | Thiophene fused azacoronenes: regioselective synthesis, self organization, charge transport, and its incorporation in conjugated polymers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-09-15 | — | — | US | disclosed |