SCHEMBL17073547

SCHEMBL17073547

c1ccc2c(c1)Nc1ccccc1-n1c-2nc2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 3/20 0.54
RAB9A P51151 3/20 0.51
ALDH1A1 P00352 10/20 0.48
KDM4E B2RXH2 10/20 0.48
HPGD P15428 8/20 0.48
GLA P06280 7/20 0.48
NPSR1 Q6W5P4 7/20 0.48
GAA P10253 6/20 0.48
MAPT P10636 6/20 0.48
HSD17B10 Q99714 6/20 0.48
CASP1 P29466 4/20 0.48
TP53 P04637 2/20 0.48
TSHR P16473 5/20 0.47
NPC1 O15118 2/20 0.47
PKM P14618 1/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2D6 P10635 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25225465 0.78 RAB9A (0.64) RAB9AALDH1A1KDM4EHPGDGLA
SCHEMBL20345687 0.75 TSHR (0.41) AKT1RAB9AALDH1A1KDM4EHPGD
SCHEMBL8900526 0.73 TSHR (0.55) RAB9AALDH1A1KDM4EHPGDMAPT
SCHEMBL9718860 0.73 RAB9A (0.53) RAB9AALDH1A1KDM4EHPGDGAA
SCHEMBL23266608 0.72 ESR1 (0.58) RAB9AALDH1A1KDM4EHPGDGAA
SCHEMBL22577608 0.72 TDO2 (0.67) RAB9AALDH1A1KDM4EHPGDMAPT
SCHEMBL24120863 0.72 RAB9A (0.51) RAB9AALDH1A1KDM4EHPGDGLA
SCHEMBL12854036 0.71 ESR1 (0.56) RAB9AALDH1A1KDM4EHPGDGAA
SCHEMBL2462367 0.71 ESR1 (0.56) RAB9AALDH1A1KDM4EHPGDGAA
SCHEMBL22522506 0.71 RAB9A (0.54) RAB9AALDH1A1KDM4EHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015133804-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-09-11 WO disclosed