Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17065802 | 0.88 | RAB9A (0.48) | RAB9AMAPTTSHRKDM4ETP53 | |
| SCHEMBL25225465 | 0.80 | RAB9A (0.64) | RAB9AMAPTTSHRKDM4ETP53 | |
| SCHEMBL221991 | 0.77 | MAPT (0.63) | RAB9AMAPTTSHRKDM4ETP53 | |
| SCHEMBL24164250 | 0.77 | NOS2 (0.46) | RAB9AMAPTTSHRKDM4ETP53 | |
| SCHEMBL8900526 | 0.74 | TSHR (0.55) | RAB9AMAPTTSHRKDM4ETP53 | |
| SCHEMBL22577608 | 0.73 | TDO2 (0.67) | RAB9AMAPTTSHRKDM4EHTT | |
| SCHEMBL23266608 | 0.73 | ESR1 (0.58) | RAB9AMAPTTSHRKDM4ETP53 | |
| SCHEMBL24120863 | 0.73 | RAB9A (0.51) | RAB9AMAPTTSHRKDM4ETP53 | |
| SCHEMBL17073547 | 0.73 | AKT1 (0.54) | RAB9AMAPTTSHRKDM4ETP53 | |
| SCHEMBL2462367 | 0.72 | ESR1 (0.56) | RAB9AMAPTTSHRKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151472-A | Dissolving polyetherimides in a solvent, adding a dianhydride and a diamine, reacting to form a polyamic acid and cyclizing to form a polyimide | GENERAL DYNAMICS CORPORATION, CONVAIR DIVISION (US) | 1992-09-29 | — | — | US | disclosed |