Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17074609 | 0.89 | CNR2 (0.81) | CNR2RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17074602 | 0.83 | RAB9A (0.85) | CNR2RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17074605 | 0.83 | CNR2 (0.70) | CNR2RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17074601 | 0.81 | CNR2 (0.67) | CNR2RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17074603 | 0.80 | CNR2 (1.00) | CNR2RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17074596 | 0.80 | CNR2 (0.66) | CNR2RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3023507 | 0.75 | RAB9A (0.72) | CNR2RAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL8243863 | 0.73 | RAB9A (0.91) | CNR2RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17074608 | 0.72 | CNR2 (0.56) | CNR2RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL17074593 | 0.71 | RAB9A (0.74) | CNR2RAB9ASMN1; SMN2NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2957560-A1 | PYRIDAZINE DERIVATIVES USEFUL AS CANNABINOID-2 AGONISTS | ALLERGAN, INC. (US) | 2015-12-23 | — | — | EP | disclosed |
| EP-2534137-B1 | PYRIDAZINE DERIVATIVES USEFUL AS CANNABINOID-2 AGONISTS | ALLERGAN INC (US) | 2015-09-16 | — | — | EP | disclosed |