Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | NAMPT | P43490 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19349021 | 0.94 | NAMPT (0.58) | RAB9AALDH1A1NAMPTHPGDLMNA | |
| SCHEMBL799425 | 0.94 | NAMPT (0.58) | RAB9AALDH1A1NAMPTHPGDLMNA | |
| SCHEMBL17865782 | 0.88 | NAMPT (0.58) | RAB9AALDH1A1NAMPTHPGDSMN1; SMN2 | |
| SCHEMBL11652211 | 0.85 | KMT2A (0.67) | RAB9AALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL11349126 | 0.83 | RAB9A (0.56) | RAB9AALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL26699525 | 0.82 | NAMPT (0.53) | RAB9AALDH1A1NAMPTHPGDLMNA | |
| SCHEMBL5940560 | 0.81 | KDM4E (0.53) | RAB9AALDH1A1NAMPTHPGDLMNA | |
| SCHEMBL8910055 | 0.81 | RAB9A (0.54) | RAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL23911908 | 0.81 | RAB9A (0.54) | RAB9AALDH1A1NAMPTHPGDLMNA | |
| SCHEMBL10912509 | 0.80 | NPC1 (0.57) | RAB9AALDH1A1HPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120089222-A1 | Photo-Activated Attachment Of Cholesterol To Polyurethane Surfaces For Adhesion Of Endothelial Cells | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2012-04-12 | — | — | US | disclosed |
| US-20120089222-A1 | Photo-Activated Attachment Of Cholesterol To Polyurethane Surfaces For Adhesion Of Endothelial Cells | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2012-04-12 | — | — | US | disclosed |