Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592711 | 0.84 | RAB9A (0.58) | RAB9AALDH1A1NPC1HDAC3HDAC1 | |
| SCHEMBL799425 | 0.83 | NAMPT (0.58) | RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL19349021 | 0.83 | NAMPT (0.58) | RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL7890971 | 0.81 | L3MBTL1 (0.48) | RAB9AALDH1A1NPC1HDAC3HDAC1 | |
| SCHEMBL1707501 | 0.81 | RAB9A (0.63) | RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL6637885 | 0.78 | HDAC3 (0.73) | RAB9ANPC1HDAC3HDAC1HDAC2 | |
| SCHEMBL4580422 | 0.78 | HDAC3 (0.35) | RAB9AALDH1A1NPC1HDAC3HDAC1 | |
| SCHEMBL20583286 | 0.78 | RAB9A (0.51) | RAB9AALDH1A1NPC1HDAC3HDAC1 | |
| SCHEMBL23982620 | 0.76 | RAB9A (0.50) | RAB9AALDH1A1NPC1HDAC3HDAC1 | |
| SCHEMBL8174154 | 0.76 | RAB9A (0.61) | RAB9AALDH1A1NPC1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659082-A | Nitro- and aminobenzamide compounds for neurodegenerative disorders | CENTAUR PHARMACEUTICALS, INC. (US) | 1997-08-19 | — | — | US | disclosed |