⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL11753229 | 0.92 | LDHA (0.47) | — | |
| SCHEMBL63335 | 0.76 | — | — | |
| Bicarbonate SCHEMBL8726606 | 0.76 | — | — | |
| Urea SCHEMBL27396614 | 0.76 | ALDH1A1 (0.60) | — | |
| Urea SCHEMBL5996634 | 0.76 | — | — | |
| Carbamic Acid SCHEMBL286743 | 0.76 | — | — | |
| Carbamic Acid SCHEMBL5903963 | 0.76 | — | — | |
| Carbamic Acid SCHEMBL11497074 | 0.76 | — | — | |
| Thiourea SCHEMBL2557219 | 0.76 | — | — | |
| Carbamic Acid SCHEMBL28066638 | 0.76 | ACHE (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552107-A | Heteroaromatic amide CYP1B1 enzyme inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2025-03-04 | — | — | CN | claimed |
| EP-3283661-B1 | PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS | JETTI RESOURCES LLC (US) | 2024-06-05 | — | — | EP | claimed |
| CN-119874696-A | Mountain nuciferine thiazole derivative and preparation method and application thereof | 南通大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-119552107-A | Heteroaromatic amide CYP1B1 enzyme inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2025-03-04 | — | — | CN | disclosed |
| CN-116354897-B | Substituted 1,2, 4-triazole, pyridine and pyrimidine derivatives and application thereof in medicines | 华东师范大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-110079524-B | Compositions and methods for modulating HBV and TTR expression | IONIS制药公司 | 2024-09-24 | — | — | CN | disclosed |
| WO-2024188107-A1 | INDOLINE COMPOUND CONTAINING THIAZOLE STRUCTURE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 沈阳药科大学 | 2024-09-19 | — | — | WO | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| EP-3555198-B1 | CURABLE POLYMER LATEX COMPOSITIONS FOR THE MANUFACTURE OF RUBBER ARTICLES | SYNTHOMER SDN BHD (MY) | 2023-09-20 | — | — | EP | disclosed |
| CN-116354897-A | Substituted 1,2, 4-triazole, pyridine and pyrimidine derivatives and application thereof in medicines | 华东师范大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-113939521-A | Imidazoline derivatives as CXCR4 modulators | 巴黎大学 | 2022-01-14 | — | — | CN | disclosed |
| US-20150259566-A1 | METHODS FOR PROVIDING A LOW GLOSS POLYURETHANE COATING ON A SUBSTRATE | BAYER MATERIALSCIENCE LLC (US) | 2015-09-17 | — | — | US | disclosed |
| WO-2015138227-A1 | METHODS FOR PROVIDING A LOW GLOSS POLYURETHANE COATING ON A SUBSTRATE | BAYER MATERIALSCIENCE LLC (US) | 2015-09-17 | — | — | WO | disclosed |