Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485615 | 0.89 | MGLL (0.44) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL4761414 | 0.84 | MGLL (0.46) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL20365061 | 0.81 | CYP1B1 (0.44) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL19703766 | 0.80 | HPGD (0.45) | ALDH1A1MAPTNPSR1HPGDTP53 | |
| SCHEMBL10147918 | 0.79 | MGLL (0.38) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL1275809 | 0.79 | CYP1B1 (0.45) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL19176752 | 0.79 | CYP1B1 (0.45) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL21419553 | 0.79 | CYP1B1 (0.45) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL12013343 | 0.78 | ALDH1A1 (0.40) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL13339063 | 0.78 | ALDH1A1 (0.37) | MGLLALDH1A1LMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845251-A1 | LINKER CONTAINING ARYLNITRO, ANTIBODY-DRUG CONJUGATE CONTAINING LINKER AND USE OF LINKER | Academy of Military Medical Sciences (CN) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020043129-A1 | LINKER CONTAINING ARYLNITRO, ANTIBODY-DRUG CONJUGATE CONTAINING LINKER AND USE OF LINKER | 中国人民解放军军事科学院军事医学研究院 | 2020-03-05 | — | — | WO | disclosed |
| WO-2019079357-A1 | TNIK MODULATORS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2019-04-25 | — | — | WO | disclosed |
| EP-2928504-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-2931316-B1 | HYDROXYL-POLYMER-DRUG-PROTEIN CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-3228325-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | Mersana Therapeutics, Inc. (US) | 2017-10-11 | — | — | EP | disclosed |
| US-20160193355-A1 | Novel linker, preparation method, and application thereof | QIN GANG (CN) | 2016-07-07 | — | — | US | disclosed |
| US-9308273-B2 | Polymer derivatives comprising an acetal or ketal branching point | NEKTAR THERAPEUTICS (US) | 2016-04-12 | — | — | US | disclosed |
| US-9102699-B2 | Sialic acid derivatives | LIPOXEN TECHNOLOGIES LIMITED (GB) | 2015-08-11 | — | — | US | disclosed |
| US-20140309409-A1 | Sialic Acid Derivatives | LIPOXEN TECHNOLOGIES LIMITED (GB) | 2014-10-16 | — | — | US | disclosed |
| US-8765936-B2 | Sialic acid derivatives | LIPOXEN TECHNOLOGIES LIMITED (GB) | 2014-07-01 | — | — | US | disclosed |
| US-8562965-B2 | Polymer derivatives comprising an acetal or ketal branching point | NEKTAR THERAPEUTICS (US) | 2013-10-22 | — | — | US | disclosed |
| US-20130096294-A1 | SIALIC ACID DERIVATIVES | LIPOXEN TECHNOLOGIES LIMITED (GB) | 2013-04-18 | — | — | US | disclosed |
| US-20120089222-A1 | Photo-Activated Attachment Of Cholesterol To Polyurethane Surfaces For Adhesion Of Endothelial Cells | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2012-04-12 | — | — | US | disclosed |
| US-20120089222-A1 | Photo-Activated Attachment Of Cholesterol To Polyurethane Surfaces For Adhesion Of Endothelial Cells | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2012-04-12 | — | — | US | disclosed |
| WO-2010118306-A1 | PHOTO-ACTIVATED ATTACHMENT OF CHOLESTEROL TO POLYURETHANE SURFACES FOR ADHESION OF ENDOTHELIAL CELLS | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309409-A1 | Sialic Acid Derivatives | NEU2, NEU4, NEU1 | MGLL 3583/4885ALDH1A1 490/4885LMNA 1911/4885 |
| US-20160193355-A1 | Novel linker, preparation method, and application thereof | ENGASE, SORT1, DNPEP | MGLL 1658/4885ALDH1A1 837/4885LMNA 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.