SCHEMBL1707604

SCHEMBL1707604

Nc1nc(N)nc(CCCc2nc(N)nc(N)n2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 1.00
CYP1A2 P05177 1/20 0.44
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
HRH4 Q9H3N8 1/20 0.34
LMNA P02545 4/20 0.32
CYP2D6 P10635 1/20 0.31
HTR1A P08908 1/20 0.31
HTR2A P28223 1/20 0.31
HTR7 P34969 1/20 0.31
HTR6 P50406 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1707515 0.94 CASP1 (0.88) CASP1CYP1A2TSHRSMN1; SMN2NPC1
SCHEMBL10454786 0.91 CASP1 (0.83) CASP1CYP1A2TSHRSMN1; SMN2NPC1
SCHEMBL11334327 0.91 CASP1 (0.83) CASP1CYP1A2TSHRSMN1; SMN2NPC1
SCHEMBL4448651 0.87 CASP1 (0.77) CASP1CYP1A2TSHRSMN1; SMN2NPC1
SCHEMBL11512959 0.84 CASP1 (0.71) CASP1CYP1A2TSHRSMN1; SMN2NPC1
SCHEMBL808441 0.84 CASP1 (0.71) CASP1CYP1A2TSHRSMN1; SMN2NPC1
SCHEMBL1639952 0.82 CASP1 (0.68) CASP1CYP1A2TSHRHRH4LMNA
SCHEMBL10673060 0.82 CASP1 (0.68) CASP1CYP1A2TSHRLMNA
SCHEMBL821896 0.80 CASP1 (0.65) CASP1TSHRSMN1; SMN2RAB9AHRH4
SCHEMBL10983992 0.80 CASP1 (0.65) CASP1TSHRSMN1; SMN2RAB9AHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025089072-A1 POLYACETAL RESIN COMPOSITION ポリプラスチックス株式会社 2025-05-01 WO disclosed
WO-2025089071-A1 POLYACETAL RESIN COMPOSITION ポリプラスチックス株式会社 2025-05-01 WO disclosed
CN-110191920-B Polyacetal resin composition 宝理塑料株式会社 2023-03-28 CN disclosed
CN-108219356-B Method for producing polyacetal resin composition 宝理塑料株式会社 2022-04-08 CN disclosed
US-11142637-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2021-10-12 US disclosed
US-20200291223-A1 POLYACETAL RESIN COMPOSITION POLYPLASTICS CO., LTD. (JP) 2020-09-17 US disclosed
US-10731027-B2 Coupled glass-fiber reinforced polyoxymethylene CELANESE SALES GERMANY GMBH (DE) 2020-08-04 US disclosed
EP-2652001-B1 COUPLED GLASS-FIBER REINFORCED POLYOXYMETHYLENE CELANESE SALES GERMANY GMBH (DE) 2018-12-26 EP disclosed
US-9540553-B2 Weather resistant polyoxymethylene compositions TICONA GMBH (DE) 2017-01-10 US disclosed
US-20160257805-A1 Coupled Glass-Fiber Reinforced Polyoxymethylene TICONA GMBH (DE) 2016-09-08 US disclosed
EP-2441786-B1 Glass-fiber reinforced polyoxymethylene TICONA GMBH (DE) 2013-07-31 EP disclosed
US-20130102718-A1 Tribologically Modified Glass-Fiber Reinforced Polyoxymethylene TICONA GMBH (DE) 2013-04-25 US disclosed
WO-2013053914-A1 TRIBOLOGICALLY MODIFIED GLASS-FIBER REINFORCED POLYOXYMETHYLENE TICONA GMBH (DE) 2013-04-18 WO disclosed
EP-2581408-A1 Tribologically modified glass-fiber reinforced polyoxymethylene Ticona GmbH (DE) 2013-04-17 EP disclosed
US-20120157588-A1 Glass Fiber-Reinforced Polyoxymethylene TICONA GMBH (DE) 2012-06-21 US disclosed
WO-2012049293-A1 COUPLED GLASS-FIBER REINFORCED POLYOXYMETHYLENE TICONA GMBH (DE) 2012-04-19 WO disclosed
EP-2441786-A1 Glass-fiber reinforced polyoxymethylene Ticona GmbH (DE) 2012-04-18 EP disclosed
US-7619020-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-11-17 US disclosed
US-20080039567-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2008-02-14 US disclosed
EP-1887043-A1 Polyacetal resin composition Polyplastics Co., Ltd. (JP) 2008-02-13 EP disclosed