Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707428 | 0.95 | PDPK1 (0.37) | POLBCCR3ALDH1A1PDPK1ABCC1 | |
| SCHEMBL1708429 | 0.91 | ROCK2 (0.42) | ROCK2CCR2ROCK1POLBCCR3 | |
| SCHEMBL1708431 | 0.91 | ROCK2 (0.42) | ROCK2CCR2ROCK1POLBCCR3 | |
| SCHEMBL1707751 | 0.89 | SLC6A3 (0.41) | CCR3ALDH1A1MAPK1KAT2BKMT2A | |
| SCHEMBL1707635 | 0.89 | ROCK2 (0.41) | ROCK2CCR2ROCK1POLBCCR3 | |
| SCHEMBL1707637 | 0.89 | ROCK2 (0.41) | ROCK2CCR2ROCK1POLBCCR3 | |
| SCHEMBL1707692 | 0.89 | KAT2B (0.40) | ROCK2CCR2ROCK1KAT2BKMT2A | |
| Hydrochloric Acid SCHEMBL1707329 | 0.89 | ROCK2 (0.40) | ROCK2CCR2ROCK1POLBCCR3 | |
| Hydrochloric Acid SCHEMBL1707327 | 0.89 | ROCK2 (0.40) | ROCK2CCR2ROCK1POLBCCR3 | |
| Hydrochloric Acid SCHEMBL1707276 | 0.89 | ROCK2 (0.40) | ROCK2CCR2ROCK1POLBCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | disclosed |