Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.68 |
| ▸ | GBA1 | P04062 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694003 | 1.00 | FUCA1 (0.68) | FUCA1GBA1ALDH1A1GRIN2BSIGMAR1 | |
| SCHEMBL1707691 | 1.00 | FUCA1 (0.68) | FUCA1GBA1ALDH1A1GRIN2BSIGMAR1 | |
| SCHEMBL1707725 | 1.00 | FUCA1 (0.68) | FUCA1GBA1ALDH1A1GRIN2BSIGMAR1 | |
| SCHEMBL12371118 | 1.00 | FUCA1 (0.68) | FUCA1GBA1ALDH1A1GRIN2BSIGMAR1 | |
| SCHEMBL30539363 | 0.93 | FUCA1 (0.64) | FUCA1GBA1ALDH1A1GRIN2BSIGMAR1 | |
| SCHEMBL694513 | 0.93 | FUCA1 (0.64) | FUCA1GBA1ALDH1A1GRIN2BSIGMAR1 | |
| SCHEMBL23939426 | 0.89 | FUCA1 (0.68) | FUCA1GBA1ALDH1A1GRIN2BSIGMAR1 | |
| SCHEMBL21561563 | 0.89 | FUCA1 (0.68) | FUCA1GBA1ALDH1A1GRIN2BSIGMAR1 | |
| SCHEMBL11413096 | 0.88 | FUCA1 (0.60) | FUCA1ALDH1A1GRIN2BSIGMAR1S1PR1 | |
| SCHEMBL16837173 | 0.86 | FUCA1 (0.58) | FUCA1GRIN2BSIGMAR1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188286-B2 | Process for production of azabicycloalkanol derivative | NIPPON SODA CO., LTD. (JP) | 2012-05-29 | — | — | US | claimed |
| US-20230357233-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-11-09 | — | — | US | disclosed |
| US-20230357233-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-11-09 | — | — | US | disclosed |
| EP-3983401-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | Arkuda Therapeutics (US) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020252222-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS (US) | 2020-12-17 | — | — | WO | disclosed |
| US-10189836-B2 | Therapeutic compounds, compositions and methods of use thereof | GENENTECH, INC. (US) | 2019-01-29 | — | — | US | disclosed |
| EP-3390402-A1 | THERAPEUTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | H. Hoffnabb-La Roche Ag (CH) | 2018-10-24 | — | — | EP | disclosed |
| US-20180297997-A1 | THERAPEUTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-10-18 | — | — | US | disclosed |
| WO-2017103188-A1 | THERAPEUTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2017-06-22 | — | — | WO | disclosed |
| EP-1932844-B1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | NIPPON SODA CO (JP) | 2015-09-02 | — | — | EP | disclosed |
| US-20090318694-A1 | Cross-Linked Amine Compounds and Agents for Pest Control | NIPPON SODA CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090318694-A1 | Cross-Linked Amine Compounds and Agents for Pest Control | NIPPON SODA CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090259045-A1 | Process for production of azabicycloalkanol derivative | NIPPON SODA CO., LTD. (JP) | 2009-10-15 | — | — | US | disclosed |
| US-20090143443-A1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2009-06-04 | — | — | US | disclosed |
| US-20090143443-A1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2009-06-04 | — | — | US | disclosed |
| US-7485727-B2 | Cyclic amine compound and pest control agent | NIPPON SODA CO., LTD. (JP) | 2009-02-03 | — | — | US | disclosed |
| US-7485727-B2 | Cyclic amine compound and pest control agent | NIPPON SODA CO., LTD. (JP) | 2009-02-03 | — | — | US | disclosed |
| EP-1932844-A1 | BRIDGED CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2008-06-18 | — | — | EP | disclosed |
| US-20080045569-A1 | Cyclic Amine Compound and Pest Control Agent | NIPPON SODA CO., LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
| US-20080045569-A1 | Cyclic Amine Compound and Pest Control Agent | NIPPON SODA CO., LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189836-B2 | Therapeutic compounds, compositions and methods of use thereof | JAK2, JAK1, JAK3 | FUCA1 2120/4885GBA1 2409/4885ALDH1A1 1702/4885 |
| US-20080045569-A1 | Cyclic Amine Compound and Pest Control Agent | H1-0, H1-2, H1-4 | FUCA1 4812/4885GBA1 4031/4885ALDH1A1 2751/4885 |
| US-20090259045-A1 | Process for production of azabicycloalkanol derivative | CYP8B1, CYP3A43, OR10J3 | FUCA1 3187/4885GBA1 2465/4885ALDH1A1 692/4885 |
| US-20090143443-A1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | TAAR1, CBR3, CBR1 | FUCA1 4794/4885GBA1 2117/4885ALDH1A1 2045/4885 |
| US-20230357233-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | KRAS, NRAS, HRAS | FUCA1 1692/4885GBA1 3153/4885ALDH1A1 1158/4885 |
| US-20180297997-A1 | THERAPEUTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | JAK2, JAK1, JAK3 | FUCA1 2120/4885GBA1 2409/4885ALDH1A1 1702/4885 |
| US-20090318694-A1 | Cross-Linked Amine Compounds and Agents for Pest Control | CYCS, NPY1R, CYBB | FUCA1 4191/4885GBA1 2245/4885ALDH1A1 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.