SCHEMBL12371118

SCHEMBL12371118

O[C@H]1[C@@H]2CC[C@H]1CN(Cc1ccccc1)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 2/20 0.68
GBA1 P04062 1/20 0.57
ALDH1A1 P00352 1/20 0.56
GRIN2B Q13224 2/20 0.50
SIGMAR1 Q99720 1/20 0.50
S1PR1 P21453 1/20 0.50
S1PR5 Q9H228 1/20 0.50
DRD2 P14416 1/20 0.49
DRD3 P35462 1/20 0.49
ACHE P22303 2/20 0.49
BCHE P06276 1/20 0.49
BACE1 P56817 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1707693 1.00 FUCA1 (0.68) FUCA1GBA1ALDH1A1GRIN2BSIGMAR1
SCHEMBL694003 1.00 FUCA1 (0.68) FUCA1GBA1ALDH1A1GRIN2BSIGMAR1
SCHEMBL1707691 1.00 FUCA1 (0.68) FUCA1GBA1ALDH1A1GRIN2BSIGMAR1
SCHEMBL1707725 1.00 FUCA1 (0.68) FUCA1GBA1ALDH1A1GRIN2BSIGMAR1
SCHEMBL30539363 0.93 FUCA1 (0.64) FUCA1GBA1ALDH1A1GRIN2BSIGMAR1
SCHEMBL694513 0.93 FUCA1 (0.64) FUCA1GBA1ALDH1A1GRIN2BSIGMAR1
SCHEMBL23939426 0.89 FUCA1 (0.68) FUCA1GBA1ALDH1A1GRIN2BSIGMAR1
SCHEMBL21561563 0.89 FUCA1 (0.68) FUCA1GBA1ALDH1A1GRIN2BSIGMAR1
SCHEMBL11413096 0.88 FUCA1 (0.60) FUCA1ALDH1A1GRIN2BSIGMAR1S1PR1
SCHEMBL16837173 0.86 FUCA1 (0.58) FUCA1GRIN2BSIGMAR1DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357233-A1 HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF InventisBio Co., Ltd. (CN) 2023-11-09 US disclosed
US-20230357233-A1 HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF InventisBio Co., Ltd. (CN) 2023-11-09 US disclosed
EP-1932844-B1 CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL NIPPON SODA CO (JP) 2015-09-02 EP disclosed
US-RE45364-E1 Cyclic amine compound and pest control agent NIPPON SODA CO., LTD. (JP) 2015-02-03 US disclosed
US-RE45364-E1 Cyclic amine compound and pest control agent NIPPON SODA CO., LTD. (JP) 2015-02-03 US disclosed
EP-1731518-B1 CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO (JP) 2014-06-25 EP disclosed
US-8536340-B2 Cross-linked cyclic amine compounds and agents for pest control NIPPON SODA CO., LTD. (JP) 2013-09-17 US disclosed
US-8536340-B2 Cross-linked cyclic amine compounds and agents for pest control NIPPON SODA CO., LTD. (JP) 2013-09-17 US disclosed
US-8101768-B2 Cyclic amine compound and pest control agent NIPPON SODA CO., LTD. (JP) 2012-01-24 US disclosed
US-8101768-B2 Cyclic amine compound and pest control agent NIPPON SODA CO., LTD. (JP) 2012-01-24 US disclosed
US-20100137582-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT OTSUKA CHEMICAL CO., LTD. (JP) 2010-06-03 US disclosed
US-20090318694-A1 Cross-Linked Amine Compounds and Agents for Pest Control NIPPON SODA CO., LTD. (JP) 2009-12-24 US disclosed
US-20090318694-A1 Cross-Linked Amine Compounds and Agents for Pest Control NIPPON SODA CO., LTD. (JP) 2009-12-24 US disclosed
US-20090143443-A1 CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2009-06-04 US disclosed
US-20090143443-A1 CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2009-06-04 US disclosed
US-7485727-B2 Cyclic amine compound and pest control agent NIPPON SODA CO., LTD. (JP) 2009-02-03 US disclosed
US-7485727-B2 Cyclic amine compound and pest control agent NIPPON SODA CO., LTD. (JP) 2009-02-03 US disclosed
EP-1932844-A1 BRIDGED CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2008-06-18 EP disclosed
US-20080045569-A1 Cyclic Amine Compound and Pest Control Agent NIPPON SODA CO., LTD. (JP) 2008-02-21 US disclosed
US-20080045569-A1 Cyclic Amine Compound and Pest Control Agent NIPPON SODA CO., LTD. (JP) 2008-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137582-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT HRH4, NOX4, PRDX4 FUCA1 4879/4885GBA1 3476/4885ALDH1A1 2550/4885
US-20080045569-A1 Cyclic Amine Compound and Pest Control Agent H1-0, H1-2, H1-4 FUCA1 4812/4885GBA1 4031/4885ALDH1A1 2751/4885
US-20090143443-A1 CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT TAAR1, CBR3, CBR1 FUCA1 4794/4885GBA1 2117/4885ALDH1A1 2045/4885
US-20230357233-A1 HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF KRAS, NRAS, HRAS FUCA1 1692/4885GBA1 3153/4885ALDH1A1 1158/4885
US-20090318694-A1 Cross-Linked Amine Compounds and Agents for Pest Control CYCS, NPY1R, CYBB FUCA1 4191/4885GBA1 2245/4885ALDH1A1 3059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.