Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TTR | P02766 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.44 |
| ▸ | TUBB | P07437 | 3/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20394912 | 1.00 | KMT2A (0.60) | KMT2AMEN1MAPTTTRKDM4E | |
| SCHEMBL2516279 | 0.98 | KMT2A (0.62) | KMT2AMEN1MAPTTTRKDM4E | |
| SCHEMBL17078207 | 0.92 | MEN1 (0.53) | KMT2AMEN1MAPTTTRKDM4E | |
| SCHEMBL2516228 | 0.92 | KMT2A (0.58) | KMT2AMEN1MAPTTTRKDM4E | |
| SCHEMBL20394921 | 0.92 | MEN1 (0.53) | KMT2AMEN1MAPTTTRKDM4E | |
| SCHEMBL18383806 | 0.90 | KMT2A (0.56) | KMT2AMEN1MAPTTTRKDM4E | |
| SCHEMBL2520244 | 0.90 | MEN1 (0.54) | KMT2AMEN1MAPTTTRKDM4E | |
| SCHEMBL2521524 | 0.88 | KMT2A (0.57) | KMT2AMEN1MAPTTTRKDM4E | |
| SCHEMBL19873150 | 0.88 | KMT2A (0.57) | KMT2AMEN1MAPTTTRKDM4E | |
| SCHEMBL18383810 | 0.87 | PTGS2 (0.54) | KMT2AMEN1MAPTTTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116849-B1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | GIULIANI SPA (IT) | 2018-07-25 | — | — | EP | claimed |
| US-9738682-B2 | Compounds with a combined antioxidant activity against free radicals together with an anti-inflammatory action, and pharmaceutical and cosmetic compositions containing them for the treatment of skin and hair | GIULIANI S.P.A. (IT) | 2017-08-22 | — | — | US | claimed |
| US-20170015700-A1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | GIULIANI S.P.A. (IT) | 2017-01-19 | — | — | US | claimed |
| EP-3116849-A1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | Giuliani S.p.A. (IT) | 2017-01-18 | — | — | EP | claimed |
| WO-2015135927-A1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | GIULIANI S.P.A. (IT) | 2015-09-17 | — | — | WO | claimed |
| EP-3116849-B1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | GIULIANI SPA (IT) | 2018-07-25 | — | — | EP | disclosed |
| EP-3116849-B1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | GIULIANI SPA (IT) | 2018-07-25 | — | — | EP | disclosed |
| US-9738682-B2 | Compounds with a combined antioxidant activity against free radicals together with an anti-inflammatory action, and pharmaceutical and cosmetic compositions containing them for the treatment of skin and hair | GIULIANI S.P.A. (IT) | 2017-08-22 | — | — | US | disclosed |
| US-9738682-B2 | Compounds with a combined antioxidant activity against free radicals together with an anti-inflammatory action, and pharmaceutical and cosmetic compositions containing them for the treatment of skin and hair | GIULIANI S.P.A. (IT) | 2017-08-22 | — | — | US | disclosed |
| US-9738682-B2 | Compounds with a combined antioxidant activity against free radicals together with an anti-inflammatory action, and pharmaceutical and cosmetic compositions containing them for the treatment of skin and hair | GIULIANI S.P.A. (IT) | 2017-08-22 | — | — | US | disclosed |
| US-20170015700-A1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | GIULIANI S.P.A. (IT) | 2017-01-19 | — | — | US | disclosed |
| US-20170015700-A1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | GIULIANI S.P.A. (IT) | 2017-01-19 | — | — | US | disclosed |
| US-20170015700-A1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | GIULIANI S.P.A. (IT) | 2017-01-19 | — | — | US | disclosed |
| EP-3116849-A1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | Giuliani S.p.A. (IT) | 2017-01-18 | — | — | EP | disclosed |
| WO-2015135927-A1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | GIULIANI S.P.A. (IT) | 2015-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015700-A1 | COMPOUNDS WITH A COMBINED ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS TOGETHER WITH AN ANTI-INFLAMMATORY ACTION, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF SKIN AND HAIR | ARG1, ARG2, TYR | KMT2A 3121/4885MEN1 4365/4885MAPT 4337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.