Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708464 | 0.90 | HAO1 (0.39) | FFAR1KDM4CHAO1GAACD274 | |
| SCHEMBL10291380 | 0.85 | FFAR1 (0.40) | FFAR1KDM4CHAO1GAATP53 | |
| SCHEMBL10009863 | 0.84 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL10291216 | 0.83 | FFAR1 (0.39) | FFAR1KDM4CHAO1GAATP53 | |
| SCHEMBL13046441 | 0.83 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL1707821 | 0.81 | KDM4C (0.37) | FFAR1KDM4CGAATDP1CD274 | |
| SCHEMBL1708367 | 0.79 | ALDH1A1 (0.36) | FFAR1KDM4CGAATDP1CD274 | |
| SCHEMBL10010697 | 0.75 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL10009860 | 0.74 | FFAR1 (0.54) | FFAR1 | |
| SCHEMBL10010108 | 0.74 | FFAR1 (0.51) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |