Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | HBB | P68871 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707821 | 0.87 | KDM4C (0.37) | ALDH1A1GAAKDM4EMAPTMEN1 | |
| SCHEMBL3722997 | 0.82 | FFAR1 (0.50) | FFAR1 | |
| SCHEMBL10291561 | 0.81 | FFAR1 (0.43) | ALDH1A1GAAKDM4EMAPTMEN1 | |
| SCHEMBL1708464 | 0.79 | HAO1 (0.39) | GAAMAPTFFAR1KDM4CRAB9A | |
| SCHEMBL1707906 | 0.79 | FFAR1 (0.38) | ALDH1A1GAAKDM4EMAPTMEN1 | |
| SCHEMBL1707705 | 0.69 | LTB4R (0.33) | LTB4RLTB4R2 | |
| SCHEMBL10011340 | 0.69 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL1708420 | 0.69 | L3MBTL1 (0.36) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL205688 | 0.69 | LTB4R (0.40) | LTB4RLTB4R2MAOB | |
| SCHEMBL204322 | 0.69 | LTB4R (0.40) | LTB4RLTB4R2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |