Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 9/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707906 | 0.90 | FFAR1 (0.38) | HAO1KDM4CFFAR1GAAMAPT | |
| SCHEMBL10291217 | 0.83 | CA12 (0.40) | HAO1CA12CA1CA2CA9 | |
| SCHEMBL10010697 | 0.83 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL1707821 | 0.82 | KDM4C (0.37) | CA2KDM4CFFAR1GAAMAPT | |
| SCHEMBL13047132 | 0.81 | FFAR1 (0.46) | HAO1CA12CA1CA2CA9 | |
| SCHEMBL1708367 | 0.79 | ALDH1A1 (0.36) | KDM4CFFAR1GAAMAPTRAB9A | |
| SCHEMBL10291218 | 0.75 | SMN1; SMN2 (0.41) | HAO1KDM4CFFAR1GAAMAPT | |
| SCHEMBL10291380 | 0.74 | FFAR1 (0.40) | HAO1KDM4CFFAR1GAAMAPT | |
| SCHEMBL10009863 | 0.74 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL10009860 | 0.73 | FFAR1 (0.54) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |