Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17080450 | 0.85 | GPR119 (0.35) | — | |
| SCHEMBL1980686 | 0.83 | BACE1 (0.34) | — | |
| SCHEMBL17080451 | 0.82 | BACE1 (0.40) | — | |
| SCHEMBL17080416 | 0.80 | BACE1 (0.39) | — | |
| SCHEMBL13861317 | 0.78 | MAPKAPK2 (0.32) | HDAC1HDAC2 | |
| SCHEMBL1993274 | 0.77 | SIRT2 (0.38) | — | |
| SCHEMBL1979811 | 0.74 | ABCC9 (0.40) | — | |
| SCHEMBL14165004 | 0.69 | BACE1 (0.58) | — | |
| SCHEMBL13859279 | 0.68 | BACE1 (0.38) | — | |
| SCHEMBL1980684 | 0.65 | BACE1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015132141-A1 | 1,3-OXAZINE-2-AMINE DERIVATIVES ACTING AS BACE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2015-09-11 | — | — | WO | disclosed |