Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645844 | 0.77 | KDM4E (0.52) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL2301745 | 0.75 | KDM4E (0.77) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL27904206 | 0.74 | KDM4E (0.56) | KDM4EALDH1A1ALOX15HSD17B10TSHR | |
| SCHEMBL8832158 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDL3MBTL1GAA | |
| SCHEMBL8832160 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDL3MBTL1GAA | |
| SCHEMBL2929292 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL4739612 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL2016630 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL24485236 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TSHRL3MBTL1GAA | |
| SCHEMBL29453685 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TSHRL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015132577-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE | LINK TECHNOLOGIES LIMITED (GB) | 2015-09-11 | — | — | WO | disclosed |