Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10010763 | 0.93 | FFAR1 (0.41) | ALDH1A1LMNAMAPTL3MBTL1FFAR1 | |
| SCHEMBL10291337 | 0.91 | TSHR (0.39) | ALDH1A1LMNAMAPTL3MBTL1FFAR1 | |
| SCHEMBL1708164 | 0.90 | FFAR1 (0.37) | ALDH1A1LMNAMAPTL3MBTL1FFAR1 | |
| SCHEMBL1708157 | 0.90 | FFAR1 (0.38) | ALDH1A1LMNAMAPTL3MBTL1FFAR1 | |
| SCHEMBL13046527 | 0.88 | DRD2 (0.44) | ALDH1A1LMNAMAPTL3MBTL1FFAR1 | |
| SCHEMBL1708146 | 0.88 | FFAR1 (0.36) | LMNAFFAR1HTTGAATSHR | |
| SCHEMBL1708632 | 0.88 | FFAR1 (0.36) | ALDH1A1LMNAL3MBTL1FFAR1HTT | |
| SCHEMBL10291221 | 0.88 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPTL3MBTL1HTT | |
| SCHEMBL1708614 | 0.88 | LMNA (0.39) | ALDH1A1LMNAMAPTFFAR1HTT | |
| SCHEMBL1708113 | 0.88 | FFAR1 (0.40) | ALDH1A1LMNAMAPTL3MBTL1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |