Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1279329 | 0.84 | MEN1 (0.60) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL8497081 | 0.83 | MEN1 (0.62) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL1279081 | 0.82 | HPGD (0.61) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL4888508 | 0.81 | ALDH1A1 (0.69) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL121529 | 0.80 | CHRM2 (0.70) | GAAALDH1A1POLBSMN1; SMN2CHRM2 | |
| SCHEMBL29207888 | 0.80 | MEN1 (0.71) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL3423616 | 0.80 | HPGD (0.58) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL28091649 | 0.80 | LTA4H (0.55) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL11014192 | 0.79 | MEN1 (0.71) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL3425734 | 0.79 | BCHE (0.71) | MEN1KMT2AALDH1A1ATMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707132-B1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | UNIV PARIS SACLAY (FR) | 2024-07-17 | — | — | EP | disclosed |
| WO-2015132427-A1 | PYRIDAZIN-3(2H)-ONE DERIVATIVES WHICH ARE SELECTIVE INHIBITORS OF THE ISOFORM B OF MONOAMINE OXIDASE | UNIVERSIDADE DE VIGO (ES) | 2015-09-11 | — | — | WO | disclosed |