Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.41 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25775983 | 0.82 | CYP1A2 (0.56) | CYP1A2CYP2C9GRIK1GRIK2MAOB | |
| SCHEMBL17080936 | 0.82 | NPC1 (0.46) | CYP1A2GRIK1GRIK2MAOBMAOA | |
| SCHEMBL17080949 | 0.82 | PAM (0.50) | CYP1A2CYP2C9MAOBKMT2ACYP2D6 | |
| SCHEMBL1787322 | 0.77 | CYP1A2 (0.50) | CYP1A2CYP2C9GRIK1GRIK2MAOB | |
| SCHEMBL18126612 | 0.77 | CYP1A2 (0.53) | CYP1A2CYP2C9GRIK1GRIK2MAOB | |
| SCHEMBL20810529 | 0.76 | TBXAS1 (0.37) | ALDH1A1 | |
| SCHEMBL20810475 | 0.75 | TBXAS1 (0.36) | ALDH1A1 | |
| SCHEMBL17080954 | 0.75 | CYP1A2 (0.44) | CYP1A2CYP2C9GRIK1GRIK2MAOB | |
| SCHEMBL2949409 | 0.74 | CYP1A2 (0.67) | CYP1A2CYP2C9MAOBMAOAHPGD | |
| SCHEMBL5477544 | 0.74 | CYP1A2 (0.67) | CYP1A2CYP2C9MAOBMAOAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896479-B2 | Functionalized naphthalene fluorophores | Kay M. Brummond (US) | 2018-02-20 | — | — | US | disclosed |
| US-9896479-B2 | Functionalized naphthalene fluorophores | Kay M. Brummond (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | BRUMMOND, KAY M | 2016-02-18 | — | — | US | disclosed |
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | BRUMMOND, KAY M | 2016-02-18 | — | — | US | disclosed |
| US-9133234-B2 | Functionalized naphthalene fluorophores | Brummond, Kay M. (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133234-B2 | Functionalized naphthalene fluorophores | Brummond, Kay M. (US) | 2015-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | NCL, SNW1, NEK1 | CYP1A2 1298/4885CYP2C9 1646/4885GRIK1 2584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.