Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17080935 | 0.86 | RAB9A (0.44) | NPC1LMNARAB9AMAPTALDH1A1 | |
| SCHEMBL17080949 | 0.83 | PAM (0.50) | NPC1LMNARAB9AMAPTALDH1A1 | |
| SCHEMBL17080951 | 0.82 | CYP1A2 (0.50) | ALDH1A1CYP1A2GRIK1GRIK2MAOB | |
| SCHEMBL7651686 | 0.77 | CYP1A2 (0.47) | NPC1LMNARAB9AMAPTALDH1A1 | |
| SCHEMBL7651688 | 0.77 | CYP1A2 (0.47) | NPC1LMNARAB9AMAPTALDH1A1 | |
| SCHEMBL17080950 | 0.75 | MEN1 (0.43) | NPC1LMNARAB9AMAPTALDH1A1 | |
| SCHEMBL5965927 | 0.74 | GRIK1 (0.44) | MAPTALDH1A1CYP1A2GRIK1GRIK2 | |
| SCHEMBL10505227 | 0.73 | TBXAS1 (0.50) | LMNAMAPTALDH1A1CYP1A2GRIK1 | |
| SCHEMBL10505231 | 0.73 | TBXAS1 (0.50) | LMNAMAPTALDH1A1CYP1A2GRIK1 | |
| SCHEMBL29260522 | 0.72 | PTGS2 (0.55) | NPC1LMNARAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896479-B2 | Functionalized naphthalene fluorophores | Kay M. Brummond (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | BRUMMOND, KAY M | 2016-02-18 | — | — | US | disclosed |
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | BRUMMOND, KAY M | 2016-02-18 | — | — | US | disclosed |
| US-9133234-B2 | Functionalized naphthalene fluorophores | Brummond, Kay M. (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133234-B2 | Functionalized naphthalene fluorophores | Brummond, Kay M. (US) | 2015-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | NCL, SNW1, NEK1 | NPC1 139/4885LMNA 217/4885RAB9A 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.