Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708362 | 0.92 | FFAR1 (0.45) | FFAR1PPARGPPARD | |
| SCHEMBL1708157 | 0.90 | FFAR1 (0.38) | FFAR1PPARDLMNAPOLBGAA | |
| SCHEMBL10291823 | 0.89 | FFAR1 (0.36) | FFAR1GAA | |
| SCHEMBL1708028 | 0.86 | FFAR1 (0.37) | FFAR1PPARD | |
| SCHEMBL1708439 | 0.86 | FFAR1 (0.40) | FFAR1PPARDLMNAPOLBGAA | |
| SCHEMBL1707998 | 0.86 | FFAR1 (0.37) | FFAR1PPARGPPARD | |
| SCHEMBL1708363 | 0.86 | INSR (0.34) | FFAR1LMNAGAA | |
| SCHEMBL1708255 | 0.85 | FFAR1 (0.40) | FFAR1PPARGPPARDLMNAPOLB | |
| SCHEMBL1708632 | 0.84 | FFAR1 (0.36) | FFAR1PPARDLMNAGAA | |
| SCHEMBL10291337 | 0.84 | TSHR (0.39) | FFAR1PPARGPPARDLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |