Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17171844 | 0.80 | L3MBTL1 (0.39) | L3MBTL1ESR1POLBGAASMN1; SMN2 | |
| SCHEMBL13723399 | 0.79 | POLB (0.47) | L3MBTL1ESR1POLBGAASMN1; SMN2 | |
| SCHEMBL17169026 | 0.77 | L3MBTL1 (0.37) | L3MBTL1ESR1POLBGAASMN1; SMN2 | |
| SCHEMBL19337848 | 0.77 | L3MBTL1 (0.34) | L3MBTL1ESR1POLBGAASMN1; SMN2 | |
| SCHEMBL17952991 | 0.73 | ROCK1 (0.35) | L3MBTL1ESR1POLBGAASMN1; SMN2 | |
| SCHEMBL19336716 | 0.73 | ROCK1 (0.35) | L3MBTL1ESR1POLBGAASMN1; SMN2 | |
| SCHEMBL17074033 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL17082259 | 0.71 | TSHR (0.33) | L3MBTL1ESR1POLBGAASMN1; SMN2 | |
| SCHEMBL17952996 | 0.71 | CHRM2 (0.34) | L3MBTL1ESR1POLBGAASMN1; SMN2 | |
| SCHEMBL17952998 | 0.70 | ESR1 (0.41) | L3MBTL1ESR1POLBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918591-A1 | NOVEL LIGAND COMPOUND, PREPARATION METHOD THEREFOR, TRANSITION METAL COMPOUND, AND PREPARATION METHOD THEREFOR | LG Chem, Ltd. (KR) | 2015-09-16 | — | — | EP | disclosed |