Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17169026 | 0.95 | L3MBTL1 (0.37) | LMNAPOLBL3MBTL1CHRM2CHRM4 | |
| SCHEMBL17169027 | 0.93 | ROCK1 (0.39) | ROCK1LMNAHSD17B10PKMHTT | |
| SCHEMBL17952997 | 0.91 | LMNA (0.31) | ROCK1LMNAHSD17B10PKMHTT | |
| SCHEMBL17952996 | 0.88 | CHRM2 (0.34) | HSD17B10HTTPOLBL3MBTL1CHRM2 | |
| SCHEMBL17952995 | 0.88 | ROCK1 (0.35) | ROCK1LMNAHSD17B10PKMHTT | |
| SCHEMBL17952986 | 0.87 | RXRA (0.33) | PKMPOLBL3MBTL1CHRM2CHRM4 | |
| SCHEMBL17952989 | 0.86 | CHRM2 (0.35) | ROCK1POLBL3MBTL1CHRM2CHRM4 | |
| SCHEMBL17952988 | 0.86 | ROCK1 (0.34) | ROCK1LMNAHSD17B10PKMHTT | |
| SCHEMBL17952992 | 0.85 | ALDH1A1 (0.37) | ROCK1LMNAHSD17B10PKMHTT | |
| SCHEMBL17952994 | 0.85 | HTR7 (0.33) | POLBL3MBTL1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790240-B2 | Ligand compound, a preparation method thereof, a transition metal compound, and a preparation method thereof | LG CHEM, LTD. (KR) | 2017-10-17 | — | — | US | disclosed |
| US-20160215004-A1 | A NOVEL LIGAND COMPOUND, A PREPARATION METHOD THEREOF, A TRANSITION METAL COMPOUND, AND A PREPARATION METHOD THEREOF | LG CHEM, LTD. (KR) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215004-A1 | A NOVEL LIGAND COMPOUND, A PREPARATION METHOD THEREOF, A TRANSITION METAL COMPOUND, AND A PREPARATION METHOD THEREOF | CD40LG, OSTC, TNFSF10 | ROCK1 3232/4885LMNA 3766/4885HSD17B10 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.