Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13723399 | 0.80 | POLB (0.47) | ESR1POLBGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL17082255 | 0.70 | L3MBTL1 (0.39) | ESR1POLBGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL27973448 | 0.70 | MTNR1A (0.53) | ESR1POLBGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL19337821 | 0.68 | ESR1 (0.37) | ESR1POLBGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL17171844 | 0.68 | L3MBTL1 (0.39) | ESR1POLBGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL15137897 | 0.66 | GAA (0.42) | ESR1POLBGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL19337848 | 0.65 | L3MBTL1 (0.34) | ESR1POLBGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL17169026 | 0.65 | L3MBTL1 (0.37) | ESR1POLBGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL14733729 | 0.65 | ROCK1 (0.50) | SMN1; SMN2LMNAMAPT | |
| SCHEMBL11995386 | 0.65 | ROCK1 (0.50) | SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160215004-A1 | A NOVEL LIGAND COMPOUND, A PREPARATION METHOD THEREOF, A TRANSITION METAL COMPOUND, AND A PREPARATION METHOD THEREOF | LG CHEM, LTD. (KR) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215004-A1 | A NOVEL LIGAND COMPOUND, A PREPARATION METHOD THEREOF, A TRANSITION METAL COMPOUND, AND A PREPARATION METHOD THEREOF | CD40LG, OSTC, TNFSF10 | ESR1 764/4885CXCR5 54/4885POLB 3045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.