Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 14/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13048877 | 0.90 | L3MBTL1 (0.54) | L3MBTL1S1PR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL23746263 | 0.89 | S1PR1 (0.53) | L3MBTL1S1PR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL23746268 | 0.85 | S1PR1 (0.49) | L3MBTL1S1PR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL23746068 | 0.81 | L3MBTL1 (0.43) | L3MBTL1S1PR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL17589730 | 0.80 | ALDH1A1 (0.44) | L3MBTL1S1PR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL23746266 | 0.80 | S1PR1 (0.50) | L3MBTL1S1PR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL17589872 | 0.79 | S1PR1 (0.41) | S1PR1KDM4ENPC1CYP1A2CYP3A4 | |
| SCHEMBL23726147 | 0.79 | HSD17B10 (0.48) | S1PR1KDM4ENPC1ALDH1A1CYP1A2 | |
| SCHEMBL18569176 | 0.79 | L3MBTL1 (0.55) | L3MBTL1S1PR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL290945 | 0.78 | HSD17B10 (0.43) | L3MBTL1S1PR1KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604268-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |