Sugi Predict

Sugi Predict / Compounds / SCHEMBL290945

SCHEMBL290945

SCHEMBL290945

CCN(C(=O)CCSC)c1sc(-c2cccnc2)nc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ HTT P42858 2/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ USP2 O75604 1/20 0.41
▸ CYP1A2 P05177 4/20 0.40
▸ CYP3A4 P08684 4/20 0.40
▸ CYP2C19 P33261 3/20 0.40
▸ LMNA P02545 1/20 0.40
▸ S1PR1 P21453 4/20 0.39
▸ CDC7 O00311 2/20 0.39
▸ DBF4 Q9UBU7 2/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23746268 0.90 S1PR1 (0.49) ALDH1A1L3MBTL1NPC1CYP1A2CYP3A4
SCHEMBL29427410 0.89 CYP1A2 (0.48) HSD17B10ALDH1A1HTTMAPK1MAPT
SCHEMBL13047975 0.89 CYP1A2 (0.48) HSD17B10ALDH1A1HTTMAPK1MAPT
SCHEMBL16653522 0.88 CYP1A2 (0.38) HSD17B10ALDH1A1HTTMAPK1MAPT
SCHEMBL13048711 0.88 ALDH1A1 (0.43) HSD17B10ALDH1A1HTTMAPK1MAPT
SCHEMBL3751454 0.88 HSD17B10 (0.43) HSD17B10ALDH1A1MAPK1MAPTCYP1A2
SCHEMBL17589730 0.88 ALDH1A1 (0.44) HSD17B10ALDH1A1HTTMAPK1MAPT
SCHEMBL13048877 0.88 L3MBTL1 (0.54) HSD17B10ALDH1A1HTTMAPK1MAPT
SCHEMBL13047561 0.87 HSD17B10 (0.46) HSD17B10ALDH1A1HTTMAPK1MAPT
SCHEMBL16651920 0.86 CDC7 (0.41) HSD17B10ALDH1A1HTTMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2024-07-11 — — US claimed
EP-4346412-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI Industries Ltd. (IN) 2024-04-10 — — EP claimed
CN-117396074-A Fungicidal compositions containing oxadiazole compounds PI工业有限公司 2024-01-12 — — CN claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 — — US claimed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 — — CN claimed
WO-2022249074-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2022-12-01 — — WO claimed
EP-3978504-A1 CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2022-04-06 — — EP claimed
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF BASF SE (DE) 2022-02-17 — — US claimed
EP-3942933-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products B.V. (NL) 2022-01-26 — — EP claimed
CN-108289456-B Mixture of cis-jasmone and bacillus amyloliquefaciens 巴斯夫欧洲公司 2022-01-11 — — CN claimed
EP-3057420-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF Agrochemical Products B.V. (NL) 2016-08-24 — — EP claimed
EP-3057419-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products B.V. (NL) 2016-08-24 — — EP claimed
EP-3057418-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products, B.V. (NL) 2016-08-24 — — EP claimed
WO-2016128261-A2 PESTICIDAL MIXTURE COMPRISING A PYRAZOLE COMPOUND, AN INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2016-08-18 — — WO claimed
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
WO-2016059240-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2016-04-21 — — WO claimed
WO-2015055757-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055755-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055752-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH HSD17B10 1723/4885ALDH1A1 913/4885HTT 3014/4885
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND NAAA, AADAC, PYCARD HSD17B10 4280/4885ALDH1A1 2621/4885HTT 501/4885
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound ATP5ME, MT-ATP6, ATP5MG HSD17B10 2044/4885ALDH1A1 3070/4885HTT 3033/4885
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS OXA1L, NOX1, NOX3 HSD17B10 563/4885ALDH1A1 63/4885HTT 3706/4885
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF MANBA, CMA1, MTX1 HSD17B10 1200/4885ALDH1A1 3619/4885HTT 1161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.