SCHEMBL17083584

SCHEMBL17083584

c1ccc(-c2ccccc2N(c2ccc(-c3ccc(-c4ccc5c6ccccc6c6ccccc6c5c4)cc3)cc2)c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.42
PLA2G2A P14555 5/20 0.37
PLA2G4A P47712 5/20 0.37
PLA2G10 O15496 1/20 0.36
GGPS1 O95749 1/20 0.35
PRKDC P78527 2/20 0.35
PIM1 P11309 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
PIM3 Q86V86 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
PTGES2 Q9H7Z7 1/20 0.33
TNKS O95271 1/20 0.32
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31
CDC14B O60729 1/20 0.31
CDC14A Q9UNH5 1/20 0.31
MEN1 O00255 1/20 0.31
CSF1R P07333 1/20 0.31
PDGFRB P09619 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26340428 0.94 ALOX5 (0.39) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL17083565 0.94 ALOX5 (0.47) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL16883075 0.94 ALOX5 (0.47) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL25621180 0.93 ALOX5 (0.46) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL27011118 0.93 ALOX5 (0.37) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL17658453 0.92 ALOX5 (0.37) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL16883029 0.91 ALOX5 (0.42) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL17083583 0.91 PLA2G2A (0.41) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL24472412 0.91 ALOX5 (0.45) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL25621201 0.91 ALOX5 (0.48) ALOX5PLA2G2APLA2G4APLA2G10GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2021-04-20 US disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME RER1, H1-2, NAP1L1 ALOX5 2443/4885PLA2G2A 3561/4885PLA2G4A 4131/4885
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same RER1, H1-2, NAP1L1 ALOX5 2443/4885PLA2G2A 3561/4885PLA2G4A 4131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.