Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367473 | 0.91 | IDO1 (0.47) | ESR1ESR2PDCD1CD274ALDH5A1 | |
| SCHEMBL9504993 | 0.85 | LCK (0.42) | MAPTKDM4EHPGDALOX15CYP3A4 | |
| SCHEMBL1420183 | 0.84 | LTA4H (0.53) | ESR2MAPTKDM4EALDH1A1ALOX15 | |
| SCHEMBL6439294 | 0.81 | MAPT (0.36) | ESR1ESR2PDCD1CD274ALDH5A1 | |
| SCHEMBL2827168 | 0.80 | TYR (0.43) | ESR1ESR2PDCD1CD274ALDH5A1 | |
| SCHEMBL14010204 | 0.79 | ESR1 (0.46) | ESR1ESR2PDCD1CD274ALDH5A1 | |
| SCHEMBL8768787 | 0.78 | GABBR2 (0.42) | MAPTALDH1A1ALOX15CYP3A4LMNA | |
| SCHEMBL15018764 | 0.77 | ESR1 (0.44) | ESR1ESR2PDCD1CD274ALDH5A1 | |
| SCHEMBL30777839 | 0.77 | MAPT (0.48) | ESR1ESR2PDCD1CD274ALDH5A1 | |
| SCHEMBL21834675 | 0.75 | ESR1 (0.44) | ESR1ESR2PDCD1CD274ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944749-B2 | Polycarbonates | SWIMC, LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944749-B2 | Polycarbonates | SWIMC, LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-20150259471-A1 | POLYCARBONATES | SWIMC LLC | 2015-09-17 | — | — | US | disclosed |
| US-20150259471-A1 | POLYCARBONATES | SWIMC LLC | 2015-09-17 | — | — | US | disclosed |