Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17083602 | 0.78 | ESR1 (0.46) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9008246 | 0.76 | ESR1 (0.59) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL8768484 | 0.76 | MAPT (0.44) | GABBR2GABBR1ALDH1A1MEN1KMT2A | |
| SCHEMBL8768071 | 0.76 | CA2 (0.44) | GABBR2GABBR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7034261 | 0.74 | GABBR2 (0.49) | GABBR2GABBR1ALDH1A1MEN1KMT2A | |
| SCHEMBL26999415 | 0.73 | ACHE (0.54) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL5486067 | 0.73 | GABBR2 (0.47) | GABBR2GABBR1ALDH1A1MEN1KMT2A | |
| SCHEMBL29678617 | 0.72 | CA2 (0.50) | GABBR2GABBR1ALDH1A1MEN1KMT2A | |
| SCHEMBL4367473 | 0.71 | IDO1 (0.47) | ALDH1A1KMT2AMAPTCYP2D6CA2 | |
| SCHEMBL9504993 | 0.70 | LCK (0.42) | MEN1KMT2AMAPTCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621255-B1 | Substituted phenoxy-isobutyric acids and esters | ADIR (FR) | 1997-08-20 | — | — | EP | disclosed |
| EP-0621255-A1 | Substituted phenoxy-isobutyric acids and esters | ADIR ET COMPAGNIE (FR) | 1994-10-26 | — | — | EP | disclosed |