SCHEMBL17083850

SCHEMBL17083850

CCCCCC[C@H](C/C=C\CCCCCCCC(=O)Oc1ccc(N=C=O)cc1)OC(=O)c1ccc(OC#N)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 1/20 0.37
▸ KMT2A Q03164 3/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ SLC22A2 O15244 1/20 0.36
▸ TMPRSS2 O15393 1/20 0.36
▸ F2 P00734 1/20 0.36
▸ F10 P00742 1/20 0.36
▸ PLG P00747 1/20 0.36
▸ F12 P00748 1/20 0.36
▸ PLAU P00749 1/20 0.36
▸ PLAT P00750 1/20 0.36
▸ KLKB1 P03952 1/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ HPN P05981 1/20 0.36
▸ CHRM2 P08172 1/20 0.36
▸ CYP2D6 P10635 1/20 0.36
▸ SLC6A2 P23975 1/20 0.36
▸ SLC6A3 Q01959 1/20 0.36
▸ KCNH2 Q12809 1/20 0.36
▸ SLC47A2 Q86VL8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17085842 0.94 KMT2A (0.40) TRPV1KMT2AMEN1SLC22A2TMPRSS2
SCHEMBL17083869 0.93 PRKCA (0.39) TRPV1KMT2APOLMPOLKPOLL
SCHEMBL17083854 0.91 PRKCA (0.36) TRPV1KMT2AMEN1SLC22A2TMPRSS2
SCHEMBL17083849 0.91 KMT2A (0.39) KMT2AMEN1SLC22A2TMPRSS2F2
SCHEMBL17083876 0.91 TRPV1 (0.37) TRPV1KMT2APOLMPOLKPOLL
SCHEMBL17083861 0.87 KMT2A (0.38) KMT2AMEN1SLC22A2TMPRSS2F2
SCHEMBL17086111 0.87 PRKCA (0.43) TRPV1KMT2APOLMPOLKPOLL
SCHEMBL17086110 0.85 PRKCA (0.39) TRPV1KMT2AMEN1SLC22A2TMPRSS2
SCHEMBL17085980 0.85 KMT2A (0.43) KMT2AMEN1SLC22A2TMPRSS2F2
SCHEMBL17086121 0.84 TRPV1 (0.40) TRPV1KMT2APOLMPOLKPOLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328192-B2 Bio-based monomers and polymers BEZWADA BIOMEDICAL, LLC (US) 2016-05-03 — — US disclosed
US-20150259464-A1 BIO-BASED MONOMERS AND POLYMERS BEZWADA BIOMEDICAL, LLC 2015-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259464-A1 BIO-BASED MONOMERS AND POLYMERS FHIT, MGAM, BPGM TRPV1 1874/4885KMT2A 4052/4885MEN1 699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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