Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 5/20 | 0.37 |
| ▸ | CHUK | O15111 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427877 | 0.87 | KDM4E (0.38) | KDM4EHSD17B10MAPTLMNAPOLB | |
| SCHEMBL15428046 | 0.86 | KDM4E (0.37) | KDM4EHSD17B10MAPTLMNAPOLB | |
| SCHEMBL15428181 | 0.79 | PRKDC (0.40) | KDM4EHSD17B10MAPTLMNATP53 | |
| SCHEMBL12145479 | 0.77 | KDM4E (0.61) | KDM4EHSD17B10MAPTLMNAPOLB | |
| SCHEMBL15428206 | 0.77 | — | — | |
| SCHEMBL12145495 | 0.76 | IKBKB (0.48) | KDM4EHSD17B10MAPTLMNAPOLB | |
| SCHEMBL15428183 | 0.76 | ALDH1A1 (0.47) | KDM4EHSD17B10MAPTLMNAPOLB | |
| SCHEMBL15428205 | 0.75 | KDM4E (0.34) | KDM4EHSD17B10MAPTLMNAPOLB | |
| SCHEMBL19670853 | 0.75 | KDM4E (0.38) | KDM4EHSD17B10MAPTLMNAPOLB | |
| SCHEMBL15427890 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-20150263297-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| US-20150263297-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150263297-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | KDM4E 3816/4885HSD17B10 2888/4885MAPT 1084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.