Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427826 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL19669299 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL15427828 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL15428271 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL26433934 | 0.87 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL15428269 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL19669293 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL15428256 | 0.86 | L3MBTL1 (0.33) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL15428261 | 0.85 | KDM4E (0.40) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL15428258 | 0.85 | KDM4E (0.34) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-20220209141-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2022-06-30 | — | — | US | disclosed |
| US-11005050-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| WO-2020212296-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-10-22 | — | — | WO | disclosed |
| EP-3328872-B1 | ELECTROLUMINESCENT BRIDGED METAL COMPLEXES FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-05-29 | — | — | EP | disclosed |
| EP-3424936-A1 | METAL COMPLEXES | Merck Patent GmbH (DE) | 2019-01-09 | — | — | EP | disclosed |
| US-20180226591-A1 | ELECTROLUMINESCENT BRIDGED METAL COMPLEXES FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180226591-A1 | ELECTROLUMINESCENT BRIDGED METAL COMPLEXES FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| WO-2017016634-A1 | ELECTROLUMINESCENT BRIDGED METAL COMPLEXES FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-02-02 | — | — | WO | disclosed |
| US-20160365520-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
| US-20160365520-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
| US-20150263297-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| US-20150263297-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| WO-2015104045-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-07-16 | — | — | WO | disclosed |
| US-20150171348-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150171348-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| WO-2014023377-A2 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-02-13 | — | — | WO | disclosed |
| WO-2014008982-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150263297-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | ALDH1A1 3721/4885KDM4E 3816/4885HPGD 3882/4885 |
| US-20150171348-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | ALDH1A1 3721/4885KDM4E 3816/4885HPGD 3882/4885 |
| US-11005050-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | ALDH1A1 3721/4885KDM4E 3816/4885HPGD 3882/4885 |
| US-20160365520-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | ALDH1A1 3721/4885KDM4E 3816/4885HPGD 3882/4885 |
| US-20220209141-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | ALDH1A1 3790/4885KDM4E 3628/4885HPGD 3841/4885 |
| US-20180226591-A1 | ELECTROLUMINESCENT BRIDGED METAL COMPLEXES FOR USE IN ELECTRONIC DEVICES | EED, SOD1, NBAS | ALDH1A1 1674/4885KDM4E 2978/4885HPGD 2480/4885 |
| US-11917901-B2 | Metal complexes | MCOLN2, MCOLN1, AP1M1 | ALDH1A1 1631/4885KDM4E 4260/4885HPGD 3283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.