Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708436 | 0.91 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL1708342 | 0.85 | NPC1 (0.35) | — | |
| SCHEMBL1707934 | 0.82 | NPC1 (0.37) | — | |
| SCHEMBL1707961 | 0.79 | GRM5 (0.32) | P2RX7GRM5 | |
| SCHEMBL1707969 | 0.78 | — | — | |
| SCHEMBL1708004 | 0.78 | KCNK3 (0.31) | — | |
| SCHEMBL3717017 | 0.78 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL1708581 | 0.78 | POLB (0.31) | — | |
| SCHEMBL1708509 | 0.77 | — | — | |
| SCHEMBL1707972 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |