Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708709 | 0.89 | SMN1; SMN2 (0.33) | SMN1; SMN2HSD17B10 | |
| SCHEMBL1707962 | 0.88 | SMN1; SMN2 (0.33) | SMN1; SMN2HSD17B10 | |
| SCHEMBL10010075 | 0.81 | PPARG (0.41) | — | |
| SCHEMBL3718334 | 0.80 | PPARG (0.33) | — | |
| SCHEMBL1708342 | 0.80 | NPC1 (0.35) | SMN1; SMN2 | |
| SCHEMBL1708500 | 0.78 | P2RX7 (0.32) | — | |
| SCHEMBL1708436 | 0.78 | P2RX7 (0.30) | — | |
| SCHEMBL1708581 | 0.77 | POLB (0.31) | SMN1; SMN2HSD17B10 | |
| SCHEMBL1708712 | 0.77 | FFAR1 (0.33) | — | |
| SCHEMBL3718064 | 0.75 | BACE1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |