Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.34 |
| ▸ | PPARD | Q03181 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708110 | 0.92 | PPARG (0.40) | TSHRMAPK1FFAR1PPARDPPARG | |
| SCHEMBL1708398 | 0.92 | PPARG (0.40) | TSHRMAPK1FFAR1PPARDPPARG | |
| SCHEMBL1707943 | 0.92 | PPARG (0.40) | TSHRMAPK1FFAR1PPARDPPARG | |
| SCHEMBL1707944 | 0.85 | TSHR (0.38) | TSHRMAPK1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL1708399 | 0.85 | TSHR (0.38) | TSHRMAPK1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL1708112 | 0.85 | TSHR (0.38) | TSHRMAPK1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL1708167 | 0.84 | PPARG (0.39) | FFAR1PPARDPPARGL3MBTL1PPARA | |
| SCHEMBL1708165 | 0.84 | FFAR1 (0.42) | FFAR1PPARDPPARGPPARA | |
| SCHEMBL1707941 | 0.84 | PPARG (0.39) | FFAR1PPARDPPARGL3MBTL1PPARA | |
| SCHEMBL1708286 | 0.83 | FFAR1 (0.40) | FFAR1PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172351-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-07-05 | — | — | US | disclosed |
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172351-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | GPR119, INSR, GLP1R | TSHR 637/4885MAPK1 326/4885SMN1; SMN2 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.