Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708707 | 0.91 | FFAR1 (0.32) | HTR1AHTR1DSLC6A4HTR1B | |
| SCHEMBL1708682 | 0.90 | BMI1 (0.32) | HTR1AHTR1DSLC6A4HTR1BL3MBTL1 | |
| SCHEMBL1708685 | 0.88 | FFAR1 (0.32) | HTR1AHTR1DSLC6A4HTR1B | |
| SCHEMBL1708671 | 0.87 | KDR (0.31) | — | |
| SCHEMBL1708355 | 0.86 | FFAR1 (0.37) | L3MBTL1 | |
| SCHEMBL1708668 | 0.86 | SCN9A (0.33) | — | |
| SCHEMBL1708716 | 0.86 | — | — | |
| SCHEMBL1708717 | 0.82 | TSHR (0.34) | L3MBTL1 | |
| SCHEMBL1708723 | 0.82 | FFAR1 (0.32) | — | |
| SCHEMBL1708043 | 0.81 | L3MBTL1 (0.33) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |