Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMI1 | P35226 | 3/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708707 | 0.93 | FFAR1 (0.32) | FFAR1ADORA2BHTR1AHTR1DSLC6A4 | |
| SCHEMBL1708723 | 0.92 | FFAR1 (0.32) | FFAR1ADORA2B | |
| SCHEMBL1708662 | 0.91 | L3MBTL1 (0.37) | FFAR1L3MBTL1 | |
| SCHEMBL1708722 | 0.90 | FFAR1 (0.34) | FFAR1 | |
| SCHEMBL1708685 | 0.90 | FFAR1 (0.32) | FFAR1ADORA2BHTR1AHTR1DSLC6A4 | |
| SCHEMBL1708708 | 0.90 | HTR1A (0.32) | HTR1AHTR1DSLC6A4HTR1BL3MBTL1 | |
| SCHEMBL1708706 | 0.90 | FFAR1 (0.31) | FFAR1 | |
| SCHEMBL1708671 | 0.89 | KDR (0.31) | FFAR1 | |
| SCHEMBL1708716 | 0.88 | — | — | |
| SCHEMBL1708668 | 0.87 | SCN9A (0.33) | BMI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |