⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18127442 | 0.78 | CHRNB2 (0.53) | — | |
| SCHEMBL17087383 | 0.75 | TGFBR1 (0.41) | — | |
| SCHEMBL1709871 | 0.73 | GRIK1 (0.37) | — | |
| SCHEMBL15909791 | 0.73 | GRIK1 (0.37) | — | |
| SCHEMBL17920045 | 0.73 | GRIK1 (0.37) | — | |
| SCHEMBL14852861 | 0.73 | GRIK1 (0.37) | — | |
| SCHEMBL13540707 | 0.73 | GRIK1 (0.37) | — | |
| SCHEMBL17524625 | 0.70 | GABRR1 (0.38) | — | |
| SCHEMBL17087471 | 0.70 | RAB9A (0.40) | — | |
| SCHEMBL18127484 | 0.70 | HTT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170007664-A1 | CYCLIC DEPSIPEPTIDE COMPOUNDS AND THEIR USES | CYPRALIS LIMITED (GB) | 2017-01-12 | — | — | US | disclosed |
| US-9382295-B2 | Cyclic depsipeptide compounds and their uses | CYPRALIS LIMITED (GB) | 2016-07-05 | — | — | US | disclosed |
| US-20150259386-A1 | CYCLIC DEPSIPEPTIDE COMPOUNDS AND THEIR USES | CYPRALIS LIMITED (GB) | 2015-09-17 | — | — | US | disclosed |