Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151590 | 0.71 | ALDH1A1 (0.59) | POLBHSD17B10SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL602671 | 0.70 | HRH4 (0.63) | HRH4HTR6 | |
| Hydrochloric Acid SCHEMBL10746200 | 0.69 | ALDH1A1 (0.57) | POLBHSD17B10SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7746480 | 0.68 | NPC1 (0.45) | HRH4SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL12044174 | 0.68 | TSHR (0.57) | HRH4IDO1TDO2TSHRTP53 | |
| SCHEMBL10346683 | 0.67 | SMN1; SMN2 (0.45) | HRH4IDO1TDO2TSHRSMN1; SMN2 | |
| SCHEMBL4729614 | 0.66 | IDO1 (0.43) | HRH4IDO1TDO2SMN1; SMN2GPR55 | |
| SCHEMBL6401649 | 0.66 | ALDH1A1 (0.53) | HRH4SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL22122037 | 0.65 | ALDH1A1 (0.49) | HRH4TSHRHSD17B10ALDH1A1NPC1 | |
| SCHEMBL754480 | 0.64 | NUDT1 (0.61) | POLBHTTSMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139573-B2 | Methods and compositions for treating anxiety | HYDRA BIOSCIENCES, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-9139573-B2 | Methods and compositions for treating anxiety | HYDRA BIOSCIENCES, INC. (US) | 2015-09-22 | — | — | US | disclosed |