SCHEMBL6401649

SCHEMBL6401649

COc1cc(N)nc(N)n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
DYRK1A Q13627 1/20 0.48
GRM4 Q14833 1/20 0.47
AURKA O14965 1/20 0.41
PDPK1 O15530 1/20 0.41
TGFBR1 P36897 1/20 0.41
ROCK1 Q13464 1/20 0.41
AURKB Q96GD4 1/20 0.41
NUDT1 P36639 1/20 0.40
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HRH4 Q9H3N8 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
ADORA2A P29274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7746480 0.88 NPC1 (0.45) ALDH1A1NPC1RAB9ADYRK1AGRM4
SCHEMBL151590 0.87 ALDH1A1 (0.59) ALDH1A1NPC1RAB9ADYRK1AGRM4
Hydrochloric Acid SCHEMBL10746200 0.85 ALDH1A1 (0.57) ALDH1A1NPC1RAB9ADYRK1AGRM4
SCHEMBL27753903 0.81 NPC1 (0.46) ALDH1A1NPC1RAB9ADYRK1AGRM4
SCHEMBL10365909 0.79 ALDH1A1 (0.52) ALDH1A1NPC1RAB9ADYRK1AGRM4
SCHEMBL504020 0.79 LMNA (0.50) ALDH1A1NPC1RAB9ADYRK1AGRM4
SCHEMBL29693606 0.79 LMNA (0.50) ALDH1A1NPC1RAB9ADYRK1AGRM4
SCHEMBL8198679 0.79 PDE2A (0.52) ALDH1A1NPC1RAB9ADYRK1AGRM4
SCHEMBL11834614 0.79 ALDH1A1 (0.46) ALDH1A1NPC1RAB9ADYRK1AGRM4
SCHEMBL754480 0.79 NUDT1 (0.61) ALDH1A1NPC1RAB9AGRM4NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026097624-A1 METHOD FOR PREPARING CHLORINE-RESISTANT NANOFILTRATION MEMBRANE, AND CHLORINE-RESISTANT NANOFILTRATION MEMBRANE PREPARED THEREWITH 沃顿科技股份有限公司 2026-05-15 WO claimed
CN-122006472-A Preparation method of chlorine-resistant nanofiltration membrane and chlorine-resistant nanofiltration membrane prepared by preparation method 沃顿科技股份有限公司 2026-05-12 CN claimed
CN-119285001-A Organic wastewater treatment agent and preparation method thereof 武汉市欣慕沛环保有限公司 2025-01-10 CN claimed
WO-2026097624-A1 METHOD FOR PREPARING CHLORINE-RESISTANT NANOFILTRATION MEMBRANE, AND CHLORINE-RESISTANT NANOFILTRATION MEMBRANE PREPARED THEREWITH 沃顿科技股份有限公司 2026-05-15 WO disclosed
CN-122006472-A Preparation method of chlorine-resistant nanofiltration membrane and chlorine-resistant nanofiltration membrane prepared by preparation method 沃顿科技股份有限公司 2026-05-12 CN disclosed
CN-119285001-B Organic wastewater treatment agent and preparation method thereof 岳朋 2025-07-01 CN disclosed
CN-119285001-A Organic wastewater treatment agent and preparation method thereof 武汉市欣慕沛环保有限公司 2025-01-10 CN disclosed
CN-119285001-A Organic wastewater treatment agent and preparation method thereof 武汉市欣慕沛环保有限公司 2025-01-10 CN disclosed
US-11935803-B2 Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-03-19 US disclosed
CN-112004845-B Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device 三菱瓦斯化学株式会社 2022-05-31 CN disclosed
US-20210401992-A1 METABOLICALLY STABLE PRODRUGS TSRL, INC. (US) 2021-12-30 US disclosed
US-20050038058-A1 Novel compounds and methods for therapy INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY 2005-02-17 US disclosed
US-6818633-B2 Antiviral for RNA or DNA viruses such as HIV, HBV or HSV; acyclic pyrimidine nucleoside phosphonate analogues; 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidine; ; alkylating the 6-hydroxypyrimidine base with a dialkyl 2-chloroethoxymethylphosphonate INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 2004-11-16 US disclosed
EP-1406911-A1 6-[2-(PHOSPHONOMETHOXY)ALKOXY]PYRIMIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 2004-04-14 EP disclosed
US-20030109499-A1 Novel compounds and methods for therapy INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ACADEMY OF SCIENCES 2003-06-12 US disclosed
WO-2003002580-A1 6-`2-(PHOSPHONOMETHOXY)ALKOXY PYRIMIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OFTHE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 2003-01-09 WO disclosed
US-4826528-A PLANT GROWTH REGULATORS CELAMERCK GMBH & CO. KG. (DE) 1989-05-02 US disclosed
US-4729995-A ANTIALLERGENS TOYO BOSEKI KABUSHIKI KAISHA (JP) 1988-03-08 US disclosed
EP-0243817-A1 Novel pyrimidine compounds Toyo Boseki Kabushiki Kaisha (JP) 1987-11-04 EP disclosed
EP-0165572-A2 Herbicidal sulfonyl urea SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038058-A1 Novel compounds and methods for therapy ZC3HAV1, IFNAR1, EIF2AK2 ALDH1A1 2417/4885NPC1 217/4885RAB9A 1823/4885
US-20210401992-A1 METABOLICALLY STABLE PRODRUGS CES1, CES2, CYP2S1 ALDH1A1 681/4885NPC1 358/4885RAB9A 3531/4885
US-20030109499-A1 Novel compounds and methods for therapy IFNAR1, ZC3HAV1, EIF2AK2 ALDH1A1 1605/4885NPC1 173/4885RAB9A 1638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.