Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27148653 | 0.81 | CYP3A4 (0.48) | CYP3A4ALDH1A1TDP1ALOX15HSD17B10 | |
| SCHEMBL3158954 | 0.81 | MAPT (0.43) | CASP1CYP3A4ALDH1A1TDP1ALOX15 | |
| SCHEMBL7589418 | 0.79 | CASP1 (0.44) | CASP1CYP3A4ALDH1A1TDP1ALOX15 | |
| Hydrochloric Acid SCHEMBL28937662 | 0.77 | CASP1 (0.42) | CASP1CYP3A4ALDH1A1TDP1ALOX15 | |
| SCHEMBL19511618 | 0.77 | MAPT (0.40) | CASP1CYP3A4ALDH1A1TDP1ALOX15 | |
| SCHEMBL16543023 | 0.77 | CASP1 (0.42) | CASP1CYP3A4ALDH1A1TDP1ALOX15 | |
| SCHEMBL15360270 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL21733236 | 0.75 | ALDH1A1 (0.54) | CYP3A4ALDH1A1TDP1ALOX15HSD17B10 | |
| SCHEMBL10140559 | 0.75 | TDP1 (0.54) | CYP3A4ALDH1A1TDP1ALOX15HSD17B10 | |
| SCHEMBL21594550 | 0.74 | PTK2 (0.38) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017028816-A1 | INDOLE DERIVATIVE, PREPARATION METHOD THEREOF, AND USE THEREOF IN PHARMACEUTICAL DRUG | 浙江海正药业股份有限公司 | 2017-02-23 | — | — | WO | disclosed |
| US-8906474-B2 | Alignment film, composition for forming alignment film and liquid crystal display device | JAPAN DISPLAY INC. (JP) | 2014-12-09 | — | — | US | disclosed |
| US-8906474-B2 | Alignment film, composition for forming alignment film and liquid crystal display device | JAPAN DISPLAY INC. (JP) | 2014-12-09 | — | — | US | disclosed |
| US-20120088040-A1 | ALIGNMENT FILM, COMPOSITION FOR FORMING ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE | MAGNOLIA WHITE CORPORATION (JP) | 2012-04-12 | — | — | US | disclosed |
| US-20120088040-A1 | ALIGNMENT FILM, COMPOSITION FOR FORMING ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE | MAGNOLIA WHITE CORPORATION (JP) | 2012-04-12 | — | — | US | disclosed |