SCHEMBL17088167

SCHEMBL17088167

CCCCCCCCCCCCCCCCCC[Si](C)(CCCN)O[Si](CCCN)(CCCCCCCCCCCCCCCCCC)CCCCCCCCCCCCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.44
TSHR P16473 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.44
EPHX1 P07099 1/20 0.44
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8409898 0.86 DNM1 (0.48) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL19956409 0.80 DNM1 (0.48) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL8409957 0.79 DNM1 (0.43) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL21114727 0.79 TSHR (0.44) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL1463435 0.78 DNM1 (0.46) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL11024773 0.76 TSHR (0.47) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL4959288 0.76 TSHR (0.47) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL7036618 0.76 TSHR (0.47) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL9859881 0.76 TSHR (0.47) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL15847538 0.74 TSHR (0.40) DNM1TSHRKMT2AALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9139770-B2 Silicone ligands for stabilizing quantum dot films NANOSYS, INC. (US) 2015-09-22 US disclosed