Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.71 |
| ▸ | ITGAM | P11215 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133011 | 0.88 | ITGB2 (0.60) | ITGB2ITGAMPOLBRAB9AALDH1A1 | |
| SCHEMBL3133014 | 0.88 | ITGB2 (0.60) | ITGB2ITGAMPOLBRAB9AALDH1A1 | |
| SCHEMBL3131533 | 0.88 | STAT3 (0.78) | ITGB2ITGAMPOLBRAB9AALDH1A1 | |
| SCHEMBL3131544 | 0.88 | STAT3 (0.78) | ITGB2ITGAMPOLBRAB9AALDH1A1 | |
| SCHEMBL3133007 | 0.88 | ITGB2 (0.60) | ITGB2ITGAMPOLBRAB9AALDH1A1 | |
| SCHEMBL3131549 | 0.88 | STAT3 (0.78) | ITGB2ITGAMPOLBRAB9AALDH1A1 | |
| SCHEMBL5146767 | 0.87 | STAT3 (0.80) | ITGB2ITGAMPOLBRAB9AALDH1A1 | |
| SCHEMBL5146772 | 0.87 | STAT3 (0.80) | ITGB2ITGAMPOLBRAB9AALDH1A1 | |
| SCHEMBL3134585 | 0.85 | MEN1 (0.63) | ITGB2ITGAMPOLBRAB9AALDH1A1 | |
| SCHEMBL3134591 | 0.85 | MEN1 (0.63) | ITGB2ITGAMPOLBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160207908-A1 | BROAD SPECTRUM ANTIVIRAL AND ANTIPARASITIC AGENTS | NIH-DEITR | 2016-07-21 | — | — | US | disclosed |
| US-20160207908-A1 | BROAD SPECTRUM ANTIVIRAL AND ANTIPARASITIC AGENTS | NIH-DEITR | 2016-07-21 | — | — | US | disclosed |
| US-9139575-B2 | Broad spectrum antiviral and antiparasitic agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-09-22 | — | — | US | disclosed |
| US-9139575-B2 | Broad spectrum antiviral and antiparasitic agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207908-A1 | BROAD SPECTRUM ANTIVIRAL AND ANTIPARASITIC AGENTS | MAVS, EIF2AK2, ZC3HAV1 | ITGB2 4322/4885ITGAM 3280/4885POLB 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.