Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420558 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL5250175 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| Hydrochloric Acid SCHEMBL2424957 | 0.98 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| Hydrochloric Acid SCHEMBL2424956 | 0.98 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| Hydrochloric Acid SCHEMBL2029100 | 0.98 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL11720401 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL500459 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL20879474 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL500460 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL24932901 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380952-A1 | Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate | UNIV PRINCETON (US) | 2021-12-09 | — | — | US | claimed |
| EP-3656855-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | The Trustees of Princeton University (US) | 2020-05-27 | — | — | EP | claimed |
| EP-2699672-B1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | UNIV PRINCETON (US) | 2019-12-25 | — | — | EP | claimed |
| US-20190218524-A1 | Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate | THE TRUSTEES OF PRINCETON UNIVERSITY | 2019-07-18 | — | — | US | claimed |
| US-20180298348-A1 | Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate | UNIV PRINCETON (US) | 2018-10-18 | — | — | US | claimed |
| US-9212349-B2 | Method to produce virus in cultured cells | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-12-15 | — | — | US | claimed |
| US-20140113353-A1 | Method to Produce Virus in Cultured Cells | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-04-24 | — | — | US | claimed |
| EP-2699672-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | The Trustees of Princeton University (US) | 2014-02-26 | — | — | EP | claimed |
| WO-2013158706-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS SUPPLEMENTED WITH ALPHA-KETOGLUTARATE | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-10-24 | — | — | WO | claimed |
| WO-2012145375-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-10-26 | — | — | WO | claimed |
| EP-1720538-B1 | METHOD FOR INDUCING CELL DEATH WITH CARBONYL SCAVENGERS | UNIV ARIZONA (US) | 2008-11-12 | — | — | EP | claimed |
| US-20210380952-A1 | Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate | UNIV PRINCETON (US) | 2021-12-09 | — | — | US | disclosed |
| WO-2020208093-A1 | CYSTEINE DERIVATIVES FOR TREATMENT AND PREVENTION OF BACTERIAL INFECTIONS | UNIVERSITY OF COPENHAGEN (DK) | 2020-10-15 | — | — | WO | disclosed |
| EP-3656855-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | The Trustees of Princeton University (US) | 2020-05-27 | — | — | EP | disclosed |
| EP-2699672-B1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | UNIV PRINCETON (US) | 2019-12-25 | — | — | EP | disclosed |
| WO-2005084659-A1 | METHOD FOR INDUCING CELL DEATH WITH CARBONYL SCAVENGERS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2005-09-15 | — | — | WO | disclosed |
| US-20050197400-A1 | Method for inducing cell death with carbonyl scavengers | NIADYNE, INC. | 2005-09-08 | — | — | US | disclosed |
| US-6294573-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPENIAS SUCH AS OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL, EPIDERMAL OR GASTRIC ULCERATION, AND TUMOR GROWTH AND METASTASIS OR INVASION | ABBOTT LABORATORIES | 2001-09-25 | — | — | US | disclosed |
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0509354-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-21 | — | — | EP | disclosed |