Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250175 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL1708960 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| Hydrochloric Acid SCHEMBL2424957 | 0.98 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| Hydrochloric Acid SCHEMBL2424956 | 0.98 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| Hydrochloric Acid SCHEMBL2029100 | 0.98 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL11720401 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL500459 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL20879474 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL500460 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1MAPTPTGS1SMN1; SMN2CA1 | |
| SCHEMBL24932901 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699672-B1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | UNIV PRINCETON (US) | 2019-12-25 | — | — | EP | claimed |
| WO-2017060914-A2 | PENICILLAMINE AND ITS DERIVATIVES ARE USED IN THE TREATMENT OF COPPER TOXICITY AND NASH | Krisani Biosciences (P) Ltd. (IN) | 2017-04-13 | — | — | WO | disclosed |
| US-9102636-B2 | Analgesic compounds, compositions, and uses thereof | GALLEON PHARMACEUTICALS, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| EP-2544542-A1 | ANALGESIC COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Galleon Pharmaceuticals, Inc. (US) | 2013-01-16 | — | — | EP | disclosed |
| US-20120202860-A2 | Analgesic Compounds, Compositions and Uses Thereof | GALLEON PHARMACEUTICALS, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| US-20110224269-A1 | Analgesic Compounds, Compositions, and Uses Thereof | GALLEON PHARMACEUTICALS, INC. | 2011-09-15 | — | — | US | disclosed |
| WO-2011112602-A1 | ANALGESIC COMPOUNDS, COMPOSITIONS, AND USES THEREOF | GALLEON PHARMACEUTICALS, INC. (US) | 2011-09-15 | — | — | WO | disclosed |
| WO-2004037159-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM | OBETHERAPY BIOTECHNOLOGY (FR) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224269-A1 | Analgesic Compounds, Compositions, and Uses Thereof | OPRL1, OPRK1, ACHE | ALDH1A1 291/4885MAPT 1007/4885PTGS1 15/4885 |
| US-20120202860-A2 | Analgesic Compounds, Compositions and Uses Thereof | OPRL1, OPRK1, ACHE | ALDH1A1 364/4885MAPT 1243/4885PTGS1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.