Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 7/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565625 | 1.00 | NPY5R (0.41) | NPY5RCNR2CRHR1NPY2RALDH1A1 | |
| SCHEMBL17090107 | 0.88 | ACHE (0.42) | ALDH1A1 | |
| SCHEMBL13564856 | 0.88 | ACHE (0.42) | ALDH1A1 | |
| SCHEMBL17090165 | 0.86 | NPC1 (0.45) | NPY5RCNR2CRHR1ALDH1A1ALDH3A1 | |
| SCHEMBL13565547 | 0.86 | NPC1 (0.45) | NPY5RCNR2CRHR1ALDH1A1ALDH3A1 | |
| SCHEMBL11935248 | 0.84 | CRHR1 (0.50) | CNR2CRHR1KCNH2CACNA1I | |
| SCHEMBL13438930 | 0.84 | CRHR1 (0.50) | CNR2CRHR1KCNH2CACNA1I | |
| SCHEMBL11935303 | 0.83 | KMT2A (0.44) | NPY5RCNR2ALDH1A1ALDH3A1 | |
| SCHEMBL17090216 | 0.83 | KMT2A (0.44) | NPY5RCNR2ALDH1A1ALDH3A1 | |
| SCHEMBL13565909 | 0.83 | NPY5R (0.38) | NPY5RCRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |